Our expertise
Deep integration of biomedical science and machine learning applied to drug discovery and translational research.
Muli-Omics Systems Biology
Integrating transcriptomics and perturbation screens
Integration of transcriptomics, single-cell data, and functional screens to identify gene programs and disease-relevant pathways.
Scientific paper:
Host Genetics of Disease Biology
Human variation and infection outcomes
Analysis of how human genetic variation influences susceptibility to infection, immune response, and disease progression.
Host Genetics of Disease Biology
Human variation and infection outcomes
Analysis of how human genetic variation influences susceptibility to infection, immune response, and disease progression.
Host Genetics of Disease Biology
Human variation and infection outcomes
Analysis of how human genetic variation influences susceptibility to infection, immune response, and disease progression.
Muli-Omics Systems Biology
Integrating transcriptomics and perturbation screens
Integration of transcriptomics, single-cell data, and functional screens to identify gene programs and disease-relevant pathways.
Scientific paper:
Host Genetics of Disease Biology
Human variation and infection outcomes
Analysis of how human genetic variation influences susceptibility to infection, immune response, and disease progression.
Host Genetics of Disease Biology
Human variation and infection outcomes
Analysis of how human genetic variation influences susceptibility to infection, immune response, and disease progression.
Host Genetics of Disease Biology
Human variation and infection outcomes
Analysis of how human genetic variation influences susceptibility to infection, immune response, and disease progression.
Discover our services. Where scientific insight meets systems engineering.
Case studies
Research Institutes
Infrastructure and analytical systems supporting large collaborative projects and multimodal biological datasets.
Exploration of Compounds in Chemical and Functional Space
Identification of bioactive metabolites that modulate macrophage differentiation (M1/M2) through high-throughput imaging screens. The project integrates metabolite fraction screening with a curated library of ~1,300 compounds to match phenotypic signatures and identify active molecules.
Metadata-driven data platforms for experimental programs
Multi-omics analysis pipelines
Integration of transcriptomics, proteomics, and imaging data
Compound annotation
From chemical and metabolite screens to macrophage biology — decoding polarization
Research Institutes
Infrastructure and analytical systems supporting large collaborative projects and multimodal biological datasets.
Exploration of Compounds in Chemical and Functional Space
Identification of bioactive metabolites that modulate macrophage differentiation (M1/M2) through high-throughput imaging screens. The project integrates metabolite fraction screening with a curated library of ~1,300 compounds to match phenotypic signatures and identify active molecules.
Metadata-driven data platforms for experimental programs
Multi-omics analysis pipelines
Integration of transcriptomics, proteomics, and imaging data
Compound annotation
From chemical and metabolite screens to macrophage biology — decoding polarization
Research Institutes
Infrastructure and analytical systems supporting large collaborative projects and multimodal biological datasets.
Exploration of Compounds in Chemical and Functional Space
Identification of bioactive metabolites that modulate macrophage differentiation (M1/M2) through high-throughput imaging screens. The project integrates metabolite fraction screening with a curated library of ~1,300 compounds to match phenotypic signatures and identify active molecules.
Metadata-driven data platforms for experimental programs
Multi-omics analysis pipelines
Integration of transcriptomics, proteomics, and imaging data
Compound annotation
From chemical and metabolite screens to macrophage biology — decoding polarization
Public Health
Computational platforms and AI systems supporting therapeutic discovery.
AI Enabled Cures Frontier (AIEC), Gates Foundation
Development of AI-enabled approaches to drug discovery for curative interventions targeting virally induced chronic diseases, with current programs focused on HPV
Collaborative AI systems
Funtional genomics and perturbation screens
CRISPR screen data integration and analysis
Interfaces for exploration and collaborative analysis
AI-accelerated novel therapies for global health challenges
Public Health
Computational platforms and AI systems supporting therapeutic discovery.
AI Enabled Cures Frontier (AIEC), Gates Foundation
Development of AI-enabled approaches to drug discovery for curative interventions targeting virally induced chronic diseases, with current programs focused on HPV
Collaborative AI systems
Funtional genomics and perturbation screens
CRISPR screen data integration and analysis
Interfaces for exploration and collaborative analysis
AI-accelerated novel therapies for global health challenges
Public Health
Computational platforms and AI systems supporting therapeutic discovery.
AI Enabled Cures Frontier (AIEC), Gates Foundation
Development of AI-enabled approaches to drug discovery for curative interventions targeting virally induced chronic diseases, with current programs focused on HPV
Collaborative AI systems
Funtional genomics and perturbation screens
CRISPR screen data integration and analysis
Interfaces for exploration and collaborative analysis
AI-accelerated novel therapies for global health challenges
Biotechnology
Computational systems supporting target identification, mechanism-of-action studies, and molecular design.
Drug Discovery
Drug Discovery integrates biological databases, pathway analysis, and LLM-enabled literature synthesis to assist scientists in generating and evaluating hypotheses across complex biological datasets.
Target discovery from perturbation screens and omics data
Mechanism-of-action inference
LLM-assisted scientific interpretation
AI-assisted literature and knowledge synthesist
Biotechnology
Computational systems supporting target identification, mechanism-of-action studies, and molecular design.
Drug Discovery
Drug Discovery integrates biological databases, pathway analysis, and LLM-enabled literature synthesis to assist scientists in generating and evaluating hypotheses across complex biological datasets.
Target discovery from perturbation screens and omics data
Mechanism-of-action inference
LLM-assisted scientific interpretation
AI-assisted literature and knowledge synthesist
Biotechnology
Computational systems supporting target identification, mechanism-of-action studies, and molecular design.
Drug Discovery
Drug Discovery integrates biological databases, pathway analysis, and LLM-enabled literature synthesis to assist scientists in generating and evaluating hypotheses across complex biological datasets.
Target discovery from perturbation screens and omics data
Mechanism-of-action inference
LLM-assisted scientific interpretation
AI-assisted literature and knowledge synthesist